
Associate Director – Health Economics & Outcomes Research, Oncology
Posted Aug 28

Posted Aug 28
This is a fully remote position, open to applicants in United States.
• Oversee the development, validation, and implementation of health economic models, including budget impact, cost-effectiveness, cost-utility, cost-consequence, ROI, decision-tree, Markov/state-transition, and partitioned-survival models.
• Create scenario and sensitivity analyses that quantify the clinical and economic value of precision diagnostics.
• Collaborate with Clinical Development, Medical Affairs, Biostatistics, and cross-functional teams to embed HEOR objectives into upcoming clinical studies.
• Integrate healthcare resource utilization, economic endpoints, patient-reported outcomes, quality-of-life assessments, cost-data collection, and real-world evidence strategies into evidence plans.
• Examine clinical-trial, observational, and real-world datasets.
• Assess resource utilization, cost of care, treatment pathways, diagnostic usage, clinical utility, comparative effectiveness, patient outcomes, survival rates, budget impact, and quality-adjusted life years.
• Direct HEOR publication strategy and produce manuscripts, abstracts, posters, oral presentations, white papers, and technical reports.
• Coordinate publication strategies with investigators, key opinion leaders, academic collaborators, and external research partners.
• Convert HEOR evidence into payer value propositions, budget impact summaries, value dossiers, reimbursement materials, health economic briefs, value calculators, and account-specific economic tools.
• Create and modify health economic evidence and payer models tailored for U.S. and international markets.
• Assist with reimbursement submissions and evidence strategies that align with HTA and payer requirements.
• Act as a strategic HEOR partner across Medical Affairs, Clinical Development, Biostatistics, Market Access, Commercial, Marketing, Regulatory, and Business Development.
• Work alongside external consultants, academic investigators, KOLs, and research partners.
• An advanced degree (PhD, PharmD, MD, DrPH, or Master's degree) in Health Economics, Outcomes Research, Epidemiology, Public Health, Biostatistics, Pharmacy, Health Services Research, or a related field.
• 5–10+ years of HEOR experience in biotechnology, pharmaceuticals, diagnostics, medical devices, consulting, academia, or a similar healthcare setting.
• Proven experience in developing and applying health economic models and conducting outcomes research using clinical-trial and/or real-world datasets.
• Background in supporting payer evidence generation, reimbursement strategy, value dossiers, market access initiatives, and scientific publications.
• Experience with precision medicine, molecular diagnostics, companion diagnostics, ctDNA, molecular residual disease (MRD), donor-derived cell-free DNA (dd-cfDNA), next-generation sequencing, biomarker-guided treatment strategies, or oncology diagnostics is highly desirable.
• Familiarity with Microsoft Excel, TreeAge Pro, R, SAS, STATA, Python, SQL, Tableau/Power BI, and statistical analysis software is preferred.
• Annual performance incentive bonus.
• Long-term equity awards.
• Comprehensive health benefits (medical, dental, vision).
• 401(k) plan with company match.
• Generous paid time off and company holidays.
• Additional wellness and work-life benefits.
• Life and disability plans for eligible employees and their dependents.
• Free testing for employees and their immediate families.
• Fertility care benefits.
• Pregnancy and baby bonding leave.
• Commuter benefits.
• Employee referral program.
Penguin Formula
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