Associate Director – Director of Product Management, Signatera Hematologic Oncology

This is a fully remote position, open to applicants in United States.

📋 Description

• Oversee the Signatera product strategy and roadmap for hematologic malignancies, starting with multiple myeloma and lymphomas.

• Create and implement the hematology product roadmap.

• Lead market entry planning for the laboratory developed test (LDT), which includes clinical validation, CLIA and state requirements, reimbursement, payer considerations, and launch readiness.

• Specify product requirements for blood-based malignancies in collaboration with R&D, Lab Operations, and Software Engineering.

• Provide product support for clinical trials utilizing Signatera in hematologic oncology, encompassing IUO studies and the transition toward IVD and regulated use.

• Collaborate with Regulatory, Clinical, and Business Development teams on trial initiation, study requirements, and companion diagnostic opportunities.

• Develop product performance metrics and dashboards; evaluate test volume, adoption, ordering trends, turnaround time, and retention rates.

• Partner with Medical Affairs and Clinical teams on evidence generation, study design, investigator recruitment, trial partnerships, publications, and presentations at congresses.

• Guide the development of Signatera Genome in hematology, including whole genome sequencing, phased variants, and structural variants.

• Conduct Voice of Customer interviews, perform market research, and gather competitive intelligence.

• Engage with key opinion leaders, advisory boards, and attend congresses such as ASH, EHA, and ASCO.

• Collaborate with Marketing on product positioning, launch strategies, pricing, and promotional materials.

• Develop business cases and financial models.

• Present strategies, progress updates, and data-driven recommendations to executive leadership.

• Perform additional duties as assigned.

⛳️ Requirements

• Bachelor’s degree in life sciences, statistics, engineering, or a related area.

• Over 5 years of experience in product management, product marketing, or market analytics within a diagnostics, biotech, or pharmaceutical organization.

• Familiarity with oncology molecular testing, next-generation sequencing (NGS), biomarkers, NGS bioinformatic workflows, and genomic data analysis.

• Experience in data analysis.

• Background in clinical trials.

• Experience in IUO and IVD regulated environments is required.

• Proven track record of bringing a molecular test to market as an LDT, including clinical validation and laboratory requirements.

• Experience in designing or supporting clinical evidence generation.

• Willingness to travel 30–40% for advisory boards, congresses, and customer meetings.

• Understanding of MRD in multiple myeloma and lymphomas.

• Knowledge of somatic variants in whole genome sequencing and MRD tracking.

• Familiarity with LDT market entry requirements and evidence for clinical adoption and payer coverage.

• Ability to convert customer and clinical needs into product specifications.

• Strong analytical capabilities with the ability to build metrics, interpret data, and present findings.

• Basic skills in financial modeling.

• Proficiency in MS Excel, Word, and PowerPoint.

• Capacity to lead without formal authority and influence cross-functional teams.

• Excellent written and verbal communication skills.

• Ability to simplify complex topics for better understanding.

• Strong focus on customer relations and building relationships with thought leaders.

• Excellent organizational and time management skills; adept at managing multiple projects and meeting deadlines.

• Availability during Pacific Time hours is required.

• Site-based presence in San Carlos, CA, Boulder, CO, or Austin, TX is preferred.

🏝️ Benefits

• Comprehensive medical, dental, vision, life, and disability plans for eligible employees and their dependents.

• Complimentary testing for employees and their immediate families.

• Fertility care benefits.

• Maternity and baby bonding leave.

• 401(k) benefits.

• Commuter benefits.

• Employee referral program.

• Flexible remote home office/hybrid office arrangement.

• A global, diverse, and inclusive workplace.