SVP Clinical Development – Global Program Lead, Pancreatic Cancer

This is a fully remote position, open to applicants in California.

📋 Description

• Provide medical leadership and oversight for development programs focused on pancreatic and colorectal cancers.

• Collaborate with the Chief Medical Officer across the Erasca portfolio.

• Lead the clinical development subteam for all gastrointestinal cancer studies.

• Design and implement innovative, efficient clinical trials while evaluating suitable endpoints.

• Oversee clinical study subteams and ensure the integrity of studies.

• Review, interpret, and communicate data related to safety and efficacy.

• Develop strategies for registration and assist with regulatory submissions and interactions with health authorities.

• Write clinical sections for INDs, NDAs, and associated documents.

• Act as medical lead and/or medical monitor for clinical programs and individual studies.

• Collaborate with Drug Safety to evaluate safety profiles of compounds.

• Author or assist in the medical components of clinical research plans, protocols, investigator brochures, clinical study reports, and regulatory submissions.

• Contribute to scientific publications and write manuscripts.

• Present findings at scientific, medical, and regulatory meetings.

• Maintain clinical and scientific expertise through literature reviews and engagement with thought leaders, investigators, stakeholders, and partners.

• Participate in due diligence and business development efforts.

• Recruit, develop, and mentor medical directors and clinical scientists.

• Build and sustain relationships across Erasca, especially with Research and Development partners and stakeholders.

• Perform responsibilities in alignment with company values, policies, and applicable regulations.

⛳️ Requirements

• M.D. degree or equivalent, with fellowship training and board certification or eligibility in Oncology or Oncology/Hematology is required.

• 8-10+ years of experience in oncology clinical trials and drug development, particularly within the pharmaceutical or biotechnology sectors.

• Proven experience as the clinical lead on late-stage clinical programs for colorectal, pancreatic, or other GI cancers is required.

• Demonstrated involvement in the clinical aspects of regulatory filings and direct communication with health authorities is required.

• Preferred experience includes exposure to early development and the transition from First-in-Human (FIH) to registration trials.

• Extensive understanding of clinical trial methodologies and the regulatory and compliance requirements that govern clinical trials.

• Proven ability to collaborate effectively across multiple functions in a matrixed team environment.

• Executive leadership skills to educate and influence stakeholders and contribute to strategic business planning and decision-making.

• Strong interpersonal, communication, influencing, and exceptional writing skills.

• Ability to achieve ambitious performance goals and meet deadlines in a dynamic environment.

• A strong learning orientation, curiosity, and dedication to science and patient care.

🏝️ Benefits

• Annual bonus.

• Equity grant upon hire and annually, allowing the option to purchase stock at a predetermined price in the future.

• Paid Time Off.

• Holiday and Sick Leave.

• Medical, Dental and Vision Plans.

• Short- and Long-Term Disability coverage.

• Basic and Voluntary Life/AD&D Coverage.

• Flexible Spending Accounts (FSA, HSA, and Commute).

• Critical Illness and Accident Coverage.

• Pet Insurance.

• Employee Assistance Program.

• 401(k) Plan with contributions from Erasca.

• Employee Stock Purchase Program.

• A casual, collaborative, and enjoyable work environment.