Senior Statistician, Research & Development

This is a fully remote position, open to applicants in United States.

📋 Description

• Take the lead on statistical design and analysis for preclinical studies, encompassing dose-response and mortality projection modeling, aging biomarker studies, enrollment/attrition, and survival modeling.

• Develop and implement population PK/PD models to aid in internal dose justification and formulation decisions.

• Perform exploratory analyses for the development of endpoints and the discovery of targets/pathways.

• Act as the statistical point of contact for preclinical studies and cross-functional R&D projects.

• Utilize survival analysis, longitudinal/mixed-effects modeling, and simulation-based power/sample size methodologies.

• Generate and enhance internal documentation and reproducible reporting utilizing Quarto/Rmarkdown.

• Assist with clinical biostatistics, comprising SAP development, regulatory strategy discussions, and drafting analysis sections.

• Collaborate with Statisticians, Clinicians, and Scientists to support CVM/FDA-ready data strategies and analysis outputs.

• Provide mentorship to junior statisticians.

• Conduct peer reviews of methodologies from external consultants, manuscripts, and cross-functional deliverables.

• Identify avenues for enhancing statistical workflows, tools, or methods across the preclinical portfolio.

• Report directly to the Statistics Manager, Research.

⛳️ Requirements

• MS or PhD in Statistics, Biostatistics, Pharmacometrics, or a related discipline.

• Over 8 years of relevant statistical experience, showcasing a proven ability to work independently on a preclinical or translational statistics portfolio.

• Practical experience in population PK/PD modeling (WinNonLin, NONMEM, nlmixr2, Monolix, or similar) – including nonlinear mixed-effects models and exposure-response analysis.

• Proven experience in experimental design, survival/longitudinal analysis, and post-hoc statistical analysis.

• A history of conducting exploratory, hypothesis-generating analysis, with the ability to navigate ambiguous data and challenge poorly defined endpoints or targets.

• Strong attention to detail and a commitment to adhering to regulatory requirements.

• Proven ability to independently learn new statistical methods, tools, or scientific domains.

• Excellent writing and communication skills, including the ability to convey information to non-statistical audiences.

• Proficiency in R and/or Python; experience with Rmarkdown/Quarto or Jupyter for reproducible reporting.

• Familiarity with AI tools (e.g., Claude code).

• Desirable: previous experience in veterinary, animal health, or translational aging research; experience with data validation pipelines; exposure to regulatory-facing statistical writing (FDA/CVM/EMA); an interest in evolving into clinical trial biostatistics over time.

• Enthusiasm for working at the cutting edge of a new category of veterinary medicine.

🏝️ Benefits

• Comprehensive health insurance – medical, dental, and vision – for you and your dependents.

• $1,000 stipend for home office equipment.

• $1,200 annual learning budget for books, courses, and more.

• $250 monthly wellness budget for gym memberships, cleaning services, spa treatments, food, and more.

• All 3-day weekends are extended to 4-day weekends.

• Unlimited vacation and paid holidays.

• Paw-ternity leave – adopt a dog and enjoy a day off with your new family member.

• Competitive salary.

• Company equity options grant for new hires.