Scientist, Genomics – Cancer Biology

This is a fully remote position, open to applicants in United States.

📋 Description

• Oversee the complete execution of multimodal genomics studies, from experimental design to data delivery.

• Plan and carry out single-cell RNA-seq, spatial transcriptomics, and spatial proteomics experiments, which include sample preparation, platform workflows, quality control, and coordination of downstream analysis.

• Convert collaborator and program inquiries into experimental designs, sample plans, and assay panels.

• Facilitate external BioPharma collaborations through study scoping, execution, communication of progress and results, reports, and presentations.

• Direct internal discovery experiments focused on cancer cell states, treatment responses, and potential biomarkers, including liquid-biopsy profiling.

• Produce NGS and relevant mass-spectrometry datasets; manage library preparation, quality control, sequencing-run management, and technical effect detection.

• Collaborate with computational scientists to integrate multimodal datasets using R and/or Python to identify signatures and prioritize candidates.

• Standardize and implement laboratory workflows, including automation in liquid handling.

• Ensure thorough documentation, sample tracking, and data provenance; contribute to standard operating procedures, technical reports, manuscripts, and patents.

• Provide mentorship and training to junior staff and collaborators as necessary.

⛳️ Requirements

• Ph.D. in Cancer Biology, Molecular Biology, Genetics/Genomics, Biochemistry, or a related discipline.

• A minimum of 1 year of relevant industry experience or completion of a postdoctoral fellowship.

• Proficiency in at least two genomic modalities.

• Experience with NGS library preparation and quality control, demonstrated through high-quality publications.

• Working knowledge of R and/or Python for genomic data analysis and visualization.

• Capability to collaborate effectively across wet-lab and computational teams.

• Strong communication skills for clearly conveying results both in writing and verbally.

• A strong motivation to apply innovative technological methods to tackle challenging biological questions.

• Preferred: Practical experience with single-cell RNA-seq, spatial transcriptomics, and/or spatial proteomics platforms, including handling of FFPE or fresh-frozen tissue.

• Preferred: Knowledge of quantitative mass spectrometry.

• Preferred: Experience with human patient tissues and preclinical models.

• Preferred: Familiarity with functional assays, such as flow cytometry, viability assessments, live-cell imaging, protein interaction, and kinase assays.

• Preferred: Ability to manage timelines and deliverables across multiple ongoing projects.

🏝️ Benefits

• Annual performance incentive bonus.

• Long-term equity awards.

• Comprehensive health benefits including medical, dental, and vision coverage.

• 401(k) plan with company matching.

• Generous paid time off and company holidays.

• Additional wellness and work-life benefits.

• Life and disability insurance plans for eligible employees and their dependents.

• Complimentary testing for employees and their immediate families.

• Fertility care benefits.

• Pregnancy and bonding leave for new parents.

• Commuter benefits.

• Employee referral program.