VP, Global Rare Disease Franchise

This is a fully remote position, open to applicants in United States.

📋 Description

• Oversee the comprehensive strategy and commercialization of REGENXBIO’s rare disease product line.

• Take ownership of the rare disease franchise's business performance and P&L, which includes revenue, profitability, forecasting, budget management, resource allocation, and commercial objectives.

• Spearhead the formulation and execution of the rare disease franchise strategy and commercialization roadmap for RGX-202 and future programs and products.

• Set business objectives, performance metrics, and operational plans.

• Manage the annual operating plan, revenue forecasts, expense budgets, and resource distribution.

• Evaluate market dynamics, competition, customer needs, and business performance to adapt strategy and investment plans accordingly.

• Collaborate with Finance and executive leadership to ensure financial rigor and accountability.

• Develop and supervise the integrated U.S. launch strategy and market entry plan for RGX-202.

• Define launch objectives, readiness milestones, performance indicators, and operational plans.

• Address challenges related to market development, patient identification and referral, treatment-center readiness, access and reimbursement, and patient onboarding.

• Oversee franchise revenue, demand generation, operational expenses, planning, forecasting, performance management, investment decisions, risks, opportunities, and sustainable growth.

• Collaborate with executive and senior leadership on global commercialization strategies and plans.

• Translate enterprise strategy into franchise priorities, operational plans, and measurable outcomes.

• Foster cross-functional alignment and accountability for commercial and franchise initiatives.

• Contribute to decisions regarding commercialization, portfolio prioritization, business development, and resource allocation.

• Represent the rare disease community in corporate strategy and decision-making processes.

• Partner with R&D on the rare neuromuscular and muscle franchise, leading cross-functional leadership and strategic planning.

• Align commercial, clinical, medical, regulatory, market access, and operational priorities.

• Utilize market, customer, patient, and competitive insights to inform pipeline strategy and development priorities.

• Provide commercial and market development insights into development plans and lifecycle strategies.

• Enhance external leadership in rare diseases through industry thought leadership, symposia, and key associations.

• Report directly to the Chief Commercial Officer.

• Lead the Rare Disease Franchise and Marketing organization.

⛳️ Requirements

• Advanced degree in relevant life sciences or finance (Ph.D., MBA, MS) is essential.

• Over 15 years of progressive commercial leadership experience in biotechnology or pharmaceuticals.

• Proven experience in leading substantial commercial teams and/or businesses.

• Demonstrated success in product launch leadership and/or significant accountability for launch strategy, readiness, and execution.

• Ability to effectively translate commercial and franchise strategy into clear business priorities and performance expectations.

• Strong business and financial acumen, with responsibilities including revenue, operating budgets, forecasting, resource allocation, and investment decisions.

• Experience operating effectively in highly cross-functional environments and influencing senior leaders across Commercial, Medical, R&D, Market Access, Finance, and other functions.

• Capability to build organizations and develop high-performing teams while leading through ambiguity and change.

• Willingness to travel as needed.

• Preferred: substantial rare disease commercial leadership experience.

• Preferred: experience in commercializing therapies with complex patient journeys, concentrated treatment-center models, and institutional access and reimbursement requirements.

• Preferred: familiarity with gene therapy, one-time therapies, biologics, and/or complex specialty treatment models.

• Preferred: experience contributing to lifecycle, pipeline, portfolio, or business-development decisions from a commercial perspective.

🏝️ Benefits

• Annual bonus program.

• Education assistance.

• Retirement plan with employer match.

• Stock options available at all levels.

• Summer hours.

• Opportunities for professional development.

• Access to development resources.

• Engaging and challenging projects.

• Competitive salary within the market.