Senior Scientist I, QSP/QST Consulting Services

This is a fully remote position, open to applicants in United States.

📋 Description

• Design, develop, test, and implement computer code to construct and sustain sub-models that represent cellular, molecular, and biochemical processes.

• Represent pharmacodynamics of compounds and/or their mechanisms of action by converting laboratory data into model parameters and curating clinical data for calibration and validation purposes.

• Acquire knowledge and effectively leverage the company’s agentic AI solutions for technical tasks.

• Lead or contribute to consulting project activities and their corresponding deliverables.

• Support R&D initiatives, which include updates to license-ready models and the development of QST models for liver injury.

• Integrate systems pharmacology modeling, software development, project management, and software maintenance.

• Create task and deliverable plans that align with the requirements of sponsor service agreements.

• Identify potential project risks and propose appropriate mitigation strategies.

• Organize meetings with both internal and external collaborators.

• Prepare reports and presentations with minimal oversight.

• Lead consulting projects after demonstrating requisite technical and project management competencies.

• Initiate departmental initiatives that promote the growth and efficiency of the QSP team.

• Engage in joint manuscript preparation and review processes.

• Manage project efforts within the confines of contracted resource allocations.

• Publish findings in scientific journals, encompassing documentation, text, figures, and correspondence with editors/peer reviewers.

• Supervise and oversee technical work, while mentoring less experienced scientists.

• Educate others on QSP/QST and related models.

• Execute additional responsibilities as assigned.

⛳️ Requirements

• Minimum of 5 years of experience in QSP/QST modeling or a demonstration of equivalent skills.

• Strong proficiency in mathematics, dynamic systems, drug development, and pharmacology.

• General understanding of relevant therapeutic areas, including clinical endpoints and the underlying principles of cell and molecular biology and/or biochemistry.

• Experience with MATLAB, THALES, Julia, SimBiology, Monolix, GastroPlus™, and/or C++ programming.

• Familiarity with PBPK, PK, popPK, and/or PKPD modeling techniques.

• Basic knowledge of large-language models and agentic AI.

• Capability to apply modeling and simulation effectively and communicate findings to non-modeling audiences.

• Excellent verbal and written communication skills.

• Strong organizational skills and the ability to multitask.

• Self-driven with the ability to work with minimal supervision.

• Willingness to travel occasionally for conferences, meetings, and training sessions.

• A Master’s degree in pharmaceutical science, biomedical engineering, or a related field in life sciences is required.

• A PhD in pharmaceutical science, biomedical engineering, or a related life sciences field is preferred.

🏝️ Benefits

• Fully remote working opportunities.

• Flexible work schedules.

• Generous vacation policy.

• Affordable health insurance coverage.

• Annual bonus incentives.

• Support for employee well-being.

• Positive company culture.