Scientist II, QSP/QST Consulting Services

atSimulations Plus, Inc.RemoteUS flagUnited StatesFull-timeUncategorizedJuniorMid-level$110k – $130k/year

Posted Oct 10

This is a fully remote position, open to applicants in United States.

📋 Description

• Design, develop, test, and implement computer code to create and maintain sub-models that represent cellular, molecular, and/or biochemical processes.

• Model compound pharmacodynamics and/or mechanism of action, converting laboratory data into model parameters and curating clinical data for calibration and validation.

• Acquire knowledge and apply the company's agentic AI solutions for technical projects.

• Play a key role in achieving the objectives of consulting projects.

• Assist in research and development initiatives, including updates to license-ready models and the creation of QST models for liver injury.

• Integrate systems pharmacology modeling with software code development, maintenance, and effective project management.

• Formulate plans and deliverables that align with sponsor service agreements.

• Organize meetings with both internal and external collaborators.

• Create presentations and reports, conduct scientific reviews, and address feedback.

• Lead consulting projects when qualified and available.

• Engage in the preparation and review of joint manuscripts.

• Oversee project efforts within the limits of contracted resources.

• Publish scientific findings, including documentation, figures, and correspondence with editors and peer reviewers.

• Train colleagues on QSP/QST and related models.

• Perform additional duties as assigned.


⛳️ Requirements

• A minimum of 2 years of experience in QSP/QST modeling or equivalent skill sets.

• Strong proficiency in mathematics, dynamic systems, and drug development processes.

• General understanding of pertinent therapeutic areas, clinical endpoints, and foundational cell and molecular biology and/or biochemistry.

• Familiarity with MATLAB, THALES, Julia, SimBiology, Monolix, GastroPlus™, and/or C++ programming.

• Experience with PBPK, PK, popPK, and/or PKPD modeling.

• Basic knowledge of large-language models and agentic AI.

• Comprehension of how to leverage modeling and simulation for optimal impact.

• Excellent verbal and written communication abilities.

• Capability to manage multiple tasks along with strong organizational skills.

• Self-driven with the capacity to work independently with minimal supervision.

• Willingness to travel occasionally for conferences, meetings, and training sessions.

• A Master's degree in pharmaceutical science, biomedical engineering, or a related field is required.

• A PhD in pharmaceutical science, biomedical engineering, or a related field is preferred.


🏝️ Benefits

• Fully remote work opportunities.

• Flexible scheduling options.

• Generous vacation policy.

• Affordable health insurance coverage.

• Annual bonus program.

• Employee well-being initiatives.

• Opportunities to publish research in scientific journals.

• Professional training and development opportunities.

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