Senior Research and Development Scientist, Algorithm Developer

This is a fully remote position, open to applicants in United States.

📋 Description

• Oversee the design, enhancement, and execution of scalable NGS algorithms and pipelines for the identification and interpretation of intricate genomic features, such as SNVs/Indels, CNVs, STRs, methylation, trisomy, PGx variants, and variations in homologous and homopolymer regions.

• Spearhead the design and refinement of targeted NGS panels for both current and new products.

• Lead the comprehensive development, validation, benchmarking, and integration of NGS algorithms and analytical pipelines utilizing both internal and public truth datasets.

• Work in close collaboration with assay scientists, bioinformatics teams, software developers, and other stakeholders to convert biological and product requirements into computational solutions.

• Offer technical and project leadership to guarantee analytical precision, reliability, scalability, and ongoing enhancement across products.

• Assist in technology transfer, pipeline updates, and production deployment, while contributing to scientific publications, conference presentations, and intellectual property initiatives.

⛳️ Requirements

• Ph.D. in Bioinformatics, Computational Biology, Genomics, or a related field.

• At least 5 years of experience in NGS algorithm development.

• Expertise in Python, R, C++, and workflow orchestration tools.

• Comprehensive knowledge of read alignment and variant calling (e.g., BWA-MEM, minimap2, GATK, DeepVariant) for germline and/or somatic variants.

• Proficiency in CNV modeling, STR detection tools, and methylation callers.

• Experience with homologous region analysis and control gene normalization.

• Knowledge in PGx variant interpretation and allele resolution.

• Familiarity with long-read technologies (ONT, PacBio) and signal-level data.

• Strong analytical, problem-solving, and communication abilities.

🏝️ Benefits

• EEO Statement: Baylor Genetics is proud to be an equal opportunity employer dedicated to building an inclusive and diverse workforce.

• We do not discriminate based on race, religion, color, national origin, sex, sexual orientation, age, gender identity, veteran status, disability, genetic information, pregnancy, childbirth, or related medical conditions, or any other status protected under applicable federal, state, or local law.