Principal Research Scientist I, Biologics CMC Developability Modeling

This is a fully remote position, open to applicants in Illinois.

📋 Description

• Act as a technical authority for modeling within the Biologics CMC Developability Team.

• Represent BCD in modeling networks throughout AbbVie and collaborate with modelers and other teams to ensure that business requirements are fulfilled by the appropriate modeling framework.

• Conduct in vitro laboratory experiments as necessary.

• Collaborate with teams to create wet lab studies that enhance models and foundational understanding of protein solution behavior.

• Recognize emerging scientific and technological developments from both internal and external sources, evaluate their significance, and incorporate relevant trends into BCD strategies and plans.

• Present findings at both internal and external professional conferences.

• Draft manuscripts for publication in peer-reviewed journals or for patent submissions.

• Potentially assume the role of BCD Lead, coordinating developability assessment activities for 1–2 Discovery Projects concurrently.

• Make cross-functional decisions across various reporting lines.

⛳️ Requirements

• BS, MS, or PhD in Pharmaceutics, Pharmaceutical Sciences, Chemistry, Chemical Engineering, or related fields.

• 14+ years of relevant industry experience with a bachelor's degree, 12+ years with a master's degree, or 6+ years with a PhD.

• Demonstrated capability to resolve critical scientific challenges.

• Direct experience in applying mechanistic or statistical modeling methods to protein long-term stability or formulation screening, such as kinetic degradation modeling.

• Proficient in predictive machine learning and statistical modeling techniques.

• Familiarity with intricate ML architectures, including deep learning and hierarchical or multi-task frameworks.

• Competent in feature attribution, sensitivity analysis, and model interpretability.

• Exceptional oral communication skills within a scientific context.

• Strong abilities in technical writing and documentation.

• Capable of working independently, adapting to changing priorities and tight deadlines for multiple tasks, identifying issues, and developing solutions.

🏝️ Benefits

• Paid time off (vacation, holidays, sick leave).

• Medical, dental, and vision insurance.

• 401(k) plan.

• Eligibility to engage in long-term incentive programs.