Principal Research Scientist I, Biologics CMC Developability Modeling

This is a fully remote position, open to applicants in Illinois.

📋 Description

• Act as a technical authority for modeling within the Biologics CMC Developability Team.

• Represent the team within AbbVie’s modeling communities and collaborate with other modelers or teams to ensure that business requirements are addressed through the appropriate modeling frameworks.

• Conduct in vitro laboratory experiments as necessary.

• Collaborate with teams to design wet-lab studies that enhance models and foundational understanding of protein solution behavior.

• Identify and evaluate emerging scientific and technological trends, assess their relevance, and incorporate applicable trends into team plans and strategies.

• Present data at both internal and external professional conferences.

• Prepare manuscripts for submission to peer-reviewed journals or patent applications.

• Serve as the BCD Lead and coordinate developability assessment activities for one to two Discovery Projects simultaneously.

• Engage in cross-functional decision-making across various reporting lines.

⛳️ Requirements

• BS, MS, or PhD in Pharmaceutics, Pharmaceutical Sciences, Chemistry, Chemical Engineering, or related fields.

• A minimum of 14 years of relevant industry experience with a bachelor's degree, 12 years with a master's degree, or 6 years with a PhD.

• Demonstrated ability to tackle critical scientific challenges.

• Direct experience in applying mechanistic or statistical modeling techniques to the long-term stability of proteins or formulation screening, such as kinetic degradation modeling.

• Proficient in predictive machine learning and statistical modeling methodologies.

• Familiarity with intricate machine learning architectures, including deep learning and hierarchical or multi-task frameworks.

• Competent in feature attribution, sensitivity analysis, and model interpretability.

• Exceptional oral communication skills within a scientific context.

• Strong technical writing and documentation abilities.

• Ability to work autonomously, adapt to shifting priorities and tight deadlines across multiple tasks, recognize problems, and pursue solutions.

🏝️ Benefits

• Paid time off (vacation, holidays, sick leave).

• Medical, dental, and vision insurance.

• 401(k) plan.

• Long-term incentive programs.

• Equal opportunity employment.