Immunology

This is a fully remote position, open to applicants in California.

📋 Description

• Act as the scientific expert on ground truth for immunology benchmarks.

• Assess the capability of AI agents to reason like professional immunologists.

• Transform actual immunology workflows into tasks with definitive answers, encompassing immune profiling, vaccine immunogenicity, T- and B-cell responses, inflammation and autoimmunity assessments, and immune cell engineering.

• Generate gold-standard responses from raw data while accounting for variability in donors, assays, and gating.

• Curate flow and spectral cytometry, single-cell and CITE-seq data, TCR/BCR repertoires, cytokine panels, serology and neutralization titers, as well as ELISpot data.

• Differentiate genuine biological signals from doublets, spillover populations, batch effects, and sampling-depth artifacts.

• Analyze immunogenicity in comparison to protection, activation versus exhaustion, and mouse findings in relation to human relevance.

• Challenge AI conclusions that would not withstand expert scrutiny.

• Identify areas where agents fall short, what an expert would do as an alternative, and what evidence could alter the conclusion.

• Encourage explicit acknowledgment of uncertainty rather than confident assumptions.

• Collaborate with scientists and engineers to develop benchmark tasks and datasets.

• Begin with a team that aligns with your expertise, with the potential to transition between teams based on performance.

⛳️ Requirements

• PhD in immunology, vaccinology, or a related discipline.

• Extensive expertise in at least one area: vaccine development, T/B cell or innate immune biology, autoimmunity, cancer immunology, inflammation, or immune cell engineering, evidenced through peer-reviewed publications or industry experience.

• Proven experience in analyzing immune data using FlowJo, R, Python, or similar tools.

• Preferred background in the industry.

• Familiarity with AI tools such as Claude, ChatGPT, or similar, with the ability to discern technically accurate yet scientifically incorrect responses.

• Strong confidence in your domain to override AI agents and willingness to adapt when corrected.

• For positions in the US: eligibility for full-time W-2 employment.

• Work authorization support is available through H-1B, O-1, TN, and STEM OPT sponsorship.

🏝️ Benefits

• $10K sign-on bonus if you start within 2 weeks of signing.

• Equity options.

• First 4 weeks (ramp) compensated at full OTE during training.

• Full OTE paid when quota cannot be justifiably applied.

• Comprehensive health, dental, and vision insurance: 100% coverage for you, 50% for dependents (for US employees).

• 401(k) plan without matching contributions (for US employees).

• Paid time off: starting with 12 days, increasing with promotions (for US employees).

• Monthly advance of 60% of OTE, which is never recouped (for contractors outside the US).

• Uncapped performance-based compensation.

• Two distinct career advancement paths: individual contributor and management.

• Regular company outings each month.

• Team off-site events.

• Catered lunches and dinners along with unlimited snacks at the San Francisco office.