Director, Commercial Strategy and Business Development

This is a fully remote position, open to applicants in Massachusetts.

📋 Description

• Oversee U.S. commercial evaluations for acquisition, licensing, partnership, and strategic business development opportunities.

• Analyze strategic alignment, unmet medical needs, treatment protocols, competitive landscape, market desirability, and long-term commercial viability.

• Support internal portfolio strategy initiatives that include new indications, lifecycle management opportunities, reformulations, and line extensions.

• Formulate recommendations regarding commercial feasibility, launch readiness, investment needs, organizational impacts, and principal risks.

• Evaluate alignment with corporate strategy and long-term growth objectives.

• Lead commercial due diligence efforts.

• Analyze epidemiology, diagnosed populations, treated populations, addressable patient demographics, treatment algorithms, and site-of-care dynamics.

• Create market sizing methodologies and opportunity assessments.

• Conduct primary and secondary research to validate hypotheses.

• Collaborate with Business Analytics to confirm epidemiology, patient opportunities, and forecasting inputs.

• Assess competitive landscapes, pipeline threats, and future market development.

• Actively participate in diligence meetings with target companies and consultants.

• Formulate pricing recommendations and commercial pricing frameworks.

• Evaluate pricing potential in relation to clinical differentiation and payer expectations.

• Develop gross-to-net assumptions and reimbursement frameworks.

• Evaluate implications of Medicare, Medicaid, Commercial, Specialty Pharmacy, and Buy-and-Bill reimbursement.

• Assess payer management expectations, utilization management risks, and access barriers.

• Evaluate coding, payment, contracting, distribution, and channel considerations.

• Assist in evaluating evolving healthcare policy initiatives and their potential effects on commercial opportunities, pricing strategies, reimbursement, and long-term asset value.

• Collaborate with Market Access leadership to analyze policy developments related to GLOBE, GUARD, GENEROUS, MFN initiatives, and other pricing and reimbursement reform efforts.

• Create analyses to assess policy-related risks and opportunities pertaining to acquisition, licensing, and portfolio opportunities.

• Support scenario planning exercises that assess the impact of policies on pricing, reimbursement, access, contracting, and commercialization assumptions.

• Work with Market Access subject matter experts to integrate policy considerations into asset evaluations and strategic recommendations.

• Formulate commercialization strategies and launch planning recommendations.

• Evaluate launch feasibility and organizational capabilities required for commercialization.

• Develop recommendations regarding sales force size, deployment models, targeting strategies, and customer engagement methods.

• Assess patient support services, HUB operations, field reimbursement, nurse educator needs, specialty pharmacy support, and distribution strategies.

• Collaborate with Finance to establish commercialization investment assumptions and operating expense estimates.

• Develop build-versus-buy recommendations and assess organizational capabilities.

• Support Market Access integration planning for acquired, licensed, or partnered assets.

• Serve as the primary Market Access liaison to the central integration management team for assigned opportunities.

• Formulate recommendations regarding Market Access integration needs, including pricing, reimbursement, patient support, contracting, distribution, field reimbursement, and access strategy considerations.

• Collaborate with cross-functional stakeholders to identify integration risks, capability gaps, resource needs, and implementation timelines.

• Assist in the development of integration workplans and readiness assessments.

• Coordinate Market Access deliverables related to integration activities and commercialization planning.

• Monitor progress against integration milestones and help identify and resolve issues.

• Provide recommendations regarding future-state operating models and organizational requirements for integrated assets.

• Develop commercial assumptions relating to pricing, reimbursement, access, uptake, competitive response, and lifecycle opportunities.

• Assist in scenario planning and sensitivity analyses.

• Collaborate with Finance and Business Development to refine revenue assumptions and investment scenarios.

• Evaluate clinical differentiation, value proposition strength, and competitive positioning.

• Assess evidence requirements necessary to support reimbursement and adoption.

• Identify evidence gaps that could affect commercial success.

• Collaborate across Business Development, Commercial, Market Access, Medical Affairs, Business Analytics, Finance, Regulatory, and Legal.

• Support leadership decision-making with objective, data-driven recommendations.

⛳️ Requirements

• A Bachelor’s degree is required.

• An MBA, MPH, PharmD, PhD, or an equivalent advanced degree is preferred.

• 8-10+ years of progressive experience in pharmaceutical, biotechnology, healthcare consulting, commercial strategy, commercial development, market access, portfolio strategy, or business development.

• Experience in conducting commercial due diligence, portfolio assessments, strategic business analyses, or asset evaluations.

• Experience in specialty pharmaceuticals or biotechnology is required.

• Strong preference for candidates with rare disease experience.

• Experience evaluating assets across various therapeutic areas.

• Experience in developing commercial assessments that support acquisition, licensing, portfolio investment, launch planning, or commercialization decisions.

• Experience assessing commercial opportunities through pricing, reimbursement, market access, commercialization requirements, operating model design, and launch readiness.

• Experience in developing commercialization plans, operating models, sales force assumptions, patient support strategies, and launch readiness assessments is preferred.

• Experience evaluating healthcare policy developments and their implications for pharmaceutical pricing, reimbursement, market access, and commercial strategy is preferred.

• Experience supporting commercial integration, launch readiness, acquisition integration, or portfolio transition activities is preferred.

• Experience working with cross-functional integration teams and organizational change initiatives is preferred.

🏝️ Benefits

• Competitive compensation for your contributions.

• Generous time-off policy.

• Summer Fridays.

• Opportunity to expand your knowledge by attending popular conferences.

• Strong emphasis on work/life balance.

• Collaborative and team-oriented work environment.

• The chance to make a positive impact on ultra-rare disease patients in need of life-saving treatments.