
Senior Software Engineer, Data & AI Solutions
Posted 3 days ago

Posted 3 days ago
This is a fully remote position, open to applicants in Texas.
• Conceptualize, develop, and sustain data products that support R&D, analytics, lab, and scientific workflows from the initial design phase to deployment and continuous improvement.
• Create and manage data pipelines for large, intricate datasets, transitioning from raw inputs to derived, analysis-ready datasets.
• Utilize knowledge in genetics and bioinformatics to craft data models, schemas, and abstractions that align with research patterns and the requirements of downstream analysis.
• Develop and enforce architectures for de-identification and privacy preservation that comply with HIPAA and relevant regulatory standards.
• Architect scalable data models for analytics, reporting, and downstream applications.
• Ensure data quality, accuracy, lineage, and observability throughout data pipelines.
• Collaborate with R&D scientists, bioinformatics teams, and software engineers to convert research requirements into reusable data assets.
• Optimize the storage, retrieval, and lifecycle management of extensive scientific files, including sequencing data and derived datasets.
• Lead rapid prototyping efforts for exploratory, proof-of-concept, and early-stage initiatives, facilitating the transition to production-grade systems.
• Apply best practices for data quality, validation, lineage, observability, and reproducibility.
• Work with product managers and domain specialists to convert requirements into technical solutions.
• Develop golden paths, templates, examples, documentation, data product catalogs, patterns, and engineering best practices.
• Offer technical guidance and mentorship to mid-level engineers.
• A Bachelor’s or Master’s degree in computer science or bioinformatics is acceptable, though experience in the healthcare or biotech data domain is preferred.
• Over 8 years of experience in data engineering, with a focus on designing and maintaining data pipelines and cloud data architectures.
• A robust background in bioinformatics, genomics, or computational biology is essential.
• Familiarity with genomics and bioinformatics formats such as BAM, VCF, and FASTQ, along with their compression, storage, delivery, and management requirements.
• Proven experience supporting scientific R&D, lab workflows, and research teams with production-quality data systems.
• High proficiency in Python, SQL, and distributed processing frameworks like Spark or their equivalents.
• Experience with orchestration tools such as Airflow, dbt, or Dagster.
• Experience with AI-assisted development tools, including LLM copilots.
• Knowledge of data products that support analytics, ML, or AI applications.
• Strong expertise in data modeling, including dimensional, normalized, and healthcare-specific schemas.
• Experience implementing CI/CD practices for data pipelines and infrastructure as code using Terraform or CloudFormation.
• Understanding of data observability, testing, and data quality frameworks.
• Proven ownership of production-quality data systems and the end-to-end pipeline lifecycle.
• Capability to assess emerging data and AI technologies and propose scalable solutions.
• Familiarity with vector databases, embeddings, semantic search, or RAG-based architectures is advantageous.
• Ability to function effectively in fast-paced environments while maintaining a balance of speed, rigor, and compliance.
• Excellent written and verbal communication skills, with the ability to collaborate across engineering, analytics, and business stakeholders.
• Experience in healthcare, life sciences, or other highly regulated data domains, including hands-on HIPAA compliance.
• A comprehensive suite of medical, dental, vision, life, and disability plans for eligible employees and their dependents.
• Complimentary testing services for Natera employees and their immediate families.
• Fertility care benefits.
• Leave for pregnancy and baby bonding.
• 401k benefits.
• Commuter benefits.
• An employee referral program.
Pluribus Digital
GoMining
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