Executive Director, Evidence Synthesis, Statistics

This is a fully remote position, open to applicants in United Kingdom.

📋 Description

• Drive and enhance RTI-HS’s Evidence Synthesis & Statistics capability, creating a leading practice centered on evidence generation, advanced analytics, and decision support.

• Act as a senior scientific consultant to pharmaceutical and biotechnology clients regarding evidence synthesis methodologies and strategies for evidence generation.

• Offer technical leadership, practical methodological input, and quality assurance across diverse evidence synthesis activities.

• Lead and actively participate in intricate analytical projects, including those that employ Bayesian methods, causal inference, patient-reported outcomes analysis, survival analysis, mixed effects/hierarchical modeling, network meta-analysis, and other indirect treatment comparisons such as matching-adjusted indirect treatment comparisons (MAICs) and simulated treatment comparisons (STCs).

• Provide guidance on integrated evidence strategies that align clinical development, HEOR, RWE, market access, and publication goals.

• Propel innovation in methodologies, ensuring the adoption of new and evolving techniques and fostering continuous improvement in delivery.

• Spearhead business development initiatives, including identifying prospects, crafting proposals, aiding client presentations and scientific meetings, and offering senior scientific insights throughout the sales process.

• Collaborate with commercial and scientific leaders within RTI-HS to enhance the visibility and reputation of the ESS capability.

• Serve as a senior client liaison, cultivating long-term relationships and providing strategic and methodological guidance across projects.

• Stay informed on industry trends, HTA, payer, and evolving JCA evidence requirements, as well as the competitive landscape to enhance service development.

• Build, mentor, coach, and nurture a high-performing team of evidence synthesis statisticians.

• Oversee project execution to ensure scientific rigor, client satisfaction, and financial success.

• Manage complex projects and portfolios, ensuring adherence to timelines, budgets, quality standards, and client expectations.

• Guarantee that appropriate tools, processes, and methodological standards are established and continuously refined.

• Promote collaboration across HEOR, RWE, Epidemiology, Market Access, and Biostatistics to deliver integrated solutions.

• Represent RTI-HS through conference presentations, publications, workshops, and webinars.

• Enhance the external scientific profile of the ESS capability through active participation with the research and HTA community, including JCA.

• Contribute to the evolution of evidence synthesis methodologies, advocating for innovative approaches that utilize AI, automation, advanced analytics, and other emerging technologies when applicable.

• Assist in the development of internal best practices, methodological guidance, and reusable intellectual capital.

⛳️ Requirements

• Advanced degree (PhD, DrPH, ScD, MD, PharmD, or equivalent) in epidemiology, health economics, biostatistics, public health, pharmacy, or a related scientific field, along with a minimum of 12+ years of pertinent experience.

• Extensive relevant experience in leading evidence synthesis activities within a pharmaceutical company, CRO, consulting firm, or academic research setting.

• Profound expertise in network meta-analysis, other indirect treatment comparison methods, advanced statistical techniques, and comprehensive evidence generation strategies.

• Proven track record of leading multidisciplinary project teams and managing complex client relationships.

• Established experience in business development, encompassing proposal leadership, client relationship management, and revenue generation.

• Strong proficiency in advanced statistical and evidence synthesis methodologies, including Bayesian techniques, network meta-analysis, other indirect treatment comparisons (e.g., MAIC), survival analysis, and health utility analysis (e.g., EQ-5D).

• Awareness of emerging methods and techniques, such as target trial emulation and evolving evidence synthesis methodologies.

• Advanced programming skills in R and/or STATA.

• Comprehensive understanding of global HTA, payer, and evolving JCA evidence requirements, and the role of evidence synthesis throughout the product lifecycle.

• Outstanding communication and presentation abilities, capable of engaging with scientific, commercial, and executive audiences.

🏝️ Benefits

• Health insurance

• Professional development opportunities