Director, Global Value and Health Economics, Outcomes Research

This is a fully remote position, open to applicants in Pennsylvania.

📋 Description

• Oversee the global and US payer evidence strategy for marketed assets within Jazz’s neurology portfolio.

• Optimize brand potential, protect value, ensure expanded access, and facilitate post-launch evidence generation.

• Formulate evidence strategies for label expansions, new formulations, line extensions, and broader patient subpopulations.

• Collaborate with Medical Affairs, Clinical Development, and Biostatistics on Phase 3b/4, pragmatic, and expanded access studies.

• Spearhead rare disease registries, natural history extensions, and post-authorization safety/efficacy studies.

• Design studies on comparative effectiveness, adherence, burden-of-illness, and real-world data.

• Co-develop HTA reassessment strategies and analytical packages with EU/INT HEOR teams.

• Direct updates to Global Value Dossiers, systematic literature reviews, and meta-analyses.

• Lead AMCP dossiers, unbranded value summaries, and state Medicaid submission dossiers.

• Create and provide training on interactive economic models and responsive scientific presentations.

• Ensure compliance of US HEOR materials with FDAMA Section 114, the 21st Century Cures Act, and FDA HCEI guidance.

• Assess outcomes-based risk-sharing agreements and frameworks for tracking real-world endpoints.

• Keep track of developments in US health policy, ICER, and value frameworks.

• Develop and implement strategies for cost-effectiveness, cost-utility, budget impact, and cost-offset modeling.

• Construct and modify economic models utilizing established clinical and real-world data.

• Act as the GVHEOR representative in IEGP governance and align evidence initiatives with brand goals.

• Collaborate with Market Access and cross-functional teams on post-launch evidence initiatives.

• Manage publications, manuscripts, and conference presentations.

• Oversee budgets, external HEOR consultancies, academic partners, and CROs.

• Provide mentorship and technical guidance to staff involved in evidence and value generation.

⛳️ Requirements

• Master’s degree (MSc, MS, MPH) or PhD in Health Economics, Outcomes Research, Pharmacoeconomics, or a closely related quantitative field.

• At least 7–10 years of experience in HEOR, Global Value, or Health Economics within the biopharmaceutical industry or a leading HEOR consulting firm.

• Extensive experience in designing and implementing post-marketing HEOR strategies, real-world comparative effectiveness studies, and evidence roadmaps that support label expansions, line extensions, and value defense.

• In-depth knowledge of the US managed care landscape and global HTA environments.

• Proven technical skills in constructing, adapting, and validating economic models, including Markov, partitioned survival, microsimulation, and dynamic budget impact models.

• Successful history of collaborating with US Market Access, Pricing/Contracting, and Payer Field Teams to create compliant customer-facing tools, interactive budget models, and AMCP dossiers.

• Demonstrated understanding of the challenges related to rare disease post-launch evidence.

• Familiarity with major US and global healthcare databases and advanced epidemiological methods.

• Proven ability to work alongside regional HEOR teams, particularly EU/INT.

• Capability to balance evidence strategy with the hands-on execution of complex technical deliverables.

• Exceptional verbal, written, and presentation skills; adept at influencing cross-functional teams and defending methodologies.

• Experience with neurology assets is preferred.

• Proven track record in leading HEOR strategy and evidence deliverables for marketed pharmaceutical products.

• Served as launch lead for at least two assets as US HEOR lead, or as a country-level HTA lead.

• Experience in conducting post-marketing RWE, patient registry studies, and economic evaluations.

• Strong record of peer-reviewed publications in health economics and outcomes research.

🏝️ Benefits

• Discretionary annual cash bonus or incentive compensation.

• Discretionary equity grants.

• Medical insurance.

• Dental insurance.

• Vision insurance.

• 401k retirement savings plan.

• Flexible paid vacation.